• AWWA WQTC71481
Provide PDF Format

Learn More

AWWA WQTC71481

  • Statistical Consideration for Validating a New Microbial Analysis Method
  • Conference Proceeding by American Water Works Association, 11/01/2009
  • Publisher: AWWA

$12.00$24.00


This paper presents a case study for the validation of a new method for detecting coliphage in groundwater samples. Coliphage is one of the microbial indicators that can be used to monitor fecalcontamination under the Ground Water Rule. This paper describes the statistical considerations required in the design of a validation study for the alternative test procedure (ATP) and performance based measurements system (PBMS) approaches. The paper evaluates the number of comparisons necessary to demonstrate equivalence or acceptability by the two approaches. Results of validation were used to demonstrate the relationship between sample size and the confidence intervals around recoveries, sensitivity (true positives), specificity (true negatives), false positives andfalse negatives between methods. This was contrasted with the relationship between sample size andthe ability to detect differences between methods using the ATP method. The design and results of aninter-laboratory validation study are presented, focusing on the sample sizes required and thedifferences that can be detected between laboratories. Includes 2 references, tables, figures.

Related Products

AWWA MTC95002

AWWA MTC95002

Funding: Key Ingredient to a Small Community Membrane System..

$12.00 $24.00

AWWA WQTC64090

AWWA WQTC64090

UV/Chlorine: Looking Beyond Conventional DBPs..

$12.00 $24.00

AWWA WQTC65951

AWWA WQTC65951

Determining the Source of Low Disinfectant Residuals Using Fluoride Tracer Protocols..

$12.00 $24.00

AWWA JAW34230

AWWA JAW34230

Journal AWWA - Assessing the Effects of Storage Tank Design on Water Quality..

$15.00 $30.00