AWWA WQTC71517

Several recent reports have documented the presence of antibiotics in drinking watersources, the result of incomplete treatment of waste streams originating from municipalsources and livestock operations. Potassium permanganate (KMnO₄) isused by a number of utilities to address a range of issues (e.g., dissolved Mn, T&O), but littleis known about the effectiveness of KMnO₄ for oxidizing antibiotics or the effect of treatmenton antibiotic potency of the treated water. This contribution reports for the first time on thetreatment of commonly detected antibiotics (trimethoprim, lincomysin, ciprofloxacin,sulfamethoxazole, sulfamethizole, and chlortetracycline) with KMnO₄. Kinetic studiesdemonstrate that KMnO₄ is a selective oxidant, exhibiting apparent second-order rateconstants with the target antibiotics at pH 7 ranging from <0.03 to 110 M^-1 s^-1. Reaction ratesare highly dependent on pH, and measured kinetic trends can be modeled by accounting forchanges in acid/base speciation of the target antibiotics. Kinetic model predictions also agreeclosely with measurements of antibiotic treatment in drinking water utility source waters ofvariable composition. Bioassay experiments show that oxidation products and intermediatespossess negligible antibacterial activity in comparison with the parent drugs. Includes 18 references, tables, figures.

Product Details

Edition:

Vol. - No.

Published:

11/01/2009

Number of Pages:

11

File Size:

1 file , 910 KB