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ToxServices GS-546

  • 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-[gamma]-2-benzopyran (HHCB) (CAS# 1222-05-5) GreenScreen for Safer Chemicals (GreenScreen) Assessment
  • Report / Survey by ToxServices LLC, 04/20/2015
  • Publisher: ToxServices

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HHCB is a chemical that functions as a fragrance ingredient. The product name Galaxolide or Galaxolide 50 (containing 50% main isomer) is the most common form of HHCB; it refers to diluted HHCB with diethyl phthalate (DEP). HHCB has a relatively complete toxicological dataset. A number of studies were conducted on Calaxolide which contains HHCB (most commonly 65%, as listed with each relevant study) and the diluent DEP or isopropyl myristate. Data on Galaxolide were also included in this GreenScreen® assessment. These data were also considered by the EU (2008) and U.S. EPA (2014) in their assessments of HHCB.

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